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Practice Standards
Guidelines for Safe Handling of Cytotoxic Drugs
 

Storage and Disposal Aspects

Scope-
This standard specifies recommendations and requirements for storage and disposal of cytotoxic drugs by pharmacy personnel.

Objective-
The objective of this standard is to provide guidelines on storage and disposal of cytotoxic drugs.

Referenced documents-
The following articles were referred to in this guideline:



ASHP Technical assistance bulletin on handling of cytotoxic and hazardous drugs. Am J Hosp Pharm 1990; 47: 1033-49


OSHA Work-practice guidelines for personnel dealing with cytotoxic (antineoplastic) drugs. Am J Hosp Pharm 1986; 43:1193-1204


SHPA Guidelines for the safe handling of cytotoxic drugs in Pharmacy Departments. Aust J Hosp Pharm 1990; 20(5): 391-4


SHPA Guidelines for the transportation and handling of cytotoxic drugs by lay personnel. Aust J Hosp Pharm 1988; 18(5): 355-91


SHPA Guidelines for the packaging of cytotoxic agents. Aust J Hosp Pharm 1986; 16(3): 156

Storage
All cytotoxic drugs must be stored in designated areas. Access to storage areas should be restricted to authorised personnel. Precaution must be taken in such facility to prevent accidental breakage. Spill kit should be made available in cytotoxic storage areas.

Disposal
1. Equipment
    Cytotoxic waste bag made of polyethylene or polypropylene, labelled     with a cytotoxic hazard label and coloured differently from other     hospital  trash bag, should be used.
    Leak-proof and punctured-proof box or sharps bin, labelled with a     cytotoxic hazard label and, if possible, coloured differently from other     hospital sharp bin, should be used for the disposal of sharp waste such     as needles, syringes and glass vials.

2. Handling
    Personnel involved in the handling of cytotoxic waste should receive     instruction on procedures for safe transport and for spill management.     These wastes must be handled separately from other hospital waste     trash and disposed of in accordance with applicable regulations.

 
 
 
 
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